FK 506 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemFK 506
CompanyTocris Bioscience, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number3631/10
Quantity10 mg
Brand/TrademarkTocris, a Bio-Techne Brand
Purity0.99
Molecular Weight804.02
Molecule Name(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-e
FormulaC₄₄H₆₉NO₁₂
StorageStore at -20°C

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(1) Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activityNPJ Parkinson's diseaseJanuary 16, 2023Ramalingam N, Jin SX, Moors TE, Fonseca-Ornelas L, Shimanaka K, Lei S, Cam HP, Watson AH, Brontesi L, Ding L, et al.

(2) RASA2 ablation in T cells boosts antigen sensitivity and long-term functionNatureSeptember 1, 2022Carnevale J, Shifrut E, Kale N, Nyberg WA, Blaeschke F, Chen YY, Li Z, Bapat SP, Diolaiti ME, O'Leary P, et al.

(3) Mild membrane depolarization in neurons induces immediate early gene transcription and acutely subdues responses to a successive stimulusThe Journal of biological chemistrySeptember 1, 2022Rienecker KDA, Poston RG, Segales JS, Finholm IW, Sono MH, Munteanu SJ, Ghaninejad-Esfahani M, Rejepova A, Tejeda-Garibay S, Wickman K, et al.

(4) Integrins Bidirectionally Regulate the Efficacy of Inhibitory Synaptic Transmission and Control GABAergic PlasticityThe Journal of neuroscience : the official journal of the Society for NeuroscienceJuly 27, 2022Wiera G, Brzdąk P, Lech AM, Lebida K, Jabłońska J, Gmerek P, Mozrzymas JW.

(6) Calcineurin Controls Cellular Prion Protein Expression in Mouse AstrocytesCellsFebruary 10, 2022Dematteis G, Restelli E, Vanella VV, Manfredi M, Marengo E, Corazzari M, Genazzani AA, Chiesa R, Lim D, Tapella L.

(7) Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicityCell reportsDecember 21, 2021Garcia JD, Gookin SE, Crosby KC, Schwartz SL, Tiemeier E, Kennedy MJ, Dell'Acqua ML, Herson PS, Quillinan N, Smith KR.

(9) Differential Regulation of ATP- and UTP-Evoked Prostaglandin E(2) and IL-6 Production from Human Airway Epithelial CellsJournal of immunology (Baltimore, Md. : 1950)September 1, 2021Kountz TS, Jairaman A, Kountz CD, Stauderman KA, Schleimer RP, Prakriya M.

(10) TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responsesNature communicationsSeptember 14, 2020Lalic T, Steponenaite A, Wei L, Vasudevan SR, Mathie A, Peirson SN, Lall GS, Cader MZ.

(11) Local miRNA-Dependent Translational Control of GABA_AR Synthesis during Inhibitory Long-Term PotentiationCell reportsJune 23, 2020Rajgor D, Purkey AM, Sanderson JL, Welle TM, Garcia JD, Dell'Acqua ML, Smith KR.

(12) BCR-Induced Ca²⁺ Signals Dynamically Tune Survival, Metabolic Reprogramming, and Proliferation of Naive B CellsCell reportsApril 14, 2020Berry CT, Liu X, Myles A, Nandi S, Chen YH, Hershberg U, Brodsky IE, Cancro MP, Lengner CJ, May MJ, et al.

(14) Roles of glycogen synthase kinase 3 alpha and calcineurin in regulating the ability of sperm to fertilize eggsFASEB journal : official publication of the Federation of American Societies for Experimental BiologyJanuary 1, 2020Dey S, Eisa A, Kline D, Wagner FF, Abeysirigunawardena S, Vijayaraghavan S.

(16) NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic ContentCell reportsJuly 9, 2019Chiu AM, Wang J, Fiske MP, Hubalkova P, Barse L, Gray JA, Sanz-Clemente A.

(17) FK506 Attenuates the MRP1-Mediated Chemoresistant Phenotype in Glioblastoma Stem-Like CellsInternational journal of molecular sciencesSeptember 11, 2018Torres Á, Arriagada V, Erices JI, Toro MLÁ, Rocha JD, Niechi I, Carrasco C, Oyarzún C, Quezada C.

(18) Methods for High-throughput Drug Combination Screening and Synergy ScoringMethods in molecular biology (Clifton, N.J.)January 1, 2018He L, Kulesskiy E, Saarela J, Turunen L, Wennerberg K, Aittokallio T, Tang J.

(19) Calcineurin Dysregulation Underlies Spinal Cord Injury-Induced K⁺ Channel Dysfunction in DRG NeuronsThe Journal of neuroscience : the official journal of the Society for NeuroscienceAugust 23, 2017Zemel BM, Muqeem T, Brown EV, Goulão M, Urban MW, Tymanskyj SR, Lepore AC, Covarrubias M.

(20) The Effects of Tacrolimus on T-Cell Proliferation Are Short-Lived: A Pilot Analysis of Immune Function TestingTransplantation directAugust 1, 2017Laskin BL, Jiao J, Baluarte HJ, Amaral S, Furth SL, Akimova T, Hancock WW, Levine MH, Reese PP, Beier UH.

FK 506